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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12379 | PD-1-IN-22 | Others , PD-1/PD-L1 | |
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM). | |||
T9907 | Nivolumab | PD-1/PD-L1 | |
Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune ... | |||
T83970 | IMMH 010 maleate | YPD-30 maleate | PD-1/PD-L1 |
IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors. | |||
T76750 | Cemiplimab | REGN-2810,SAR-439684 | Others |
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance... | |||
T40111L | BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride | PD-1/PD-L1 | |
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi... | |||
T12387 | PD1-PDL1-IN 1 | Others | |
PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator. | |||
T70291 | PCC0208018 | ||
PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programm... | |||
T61750 | Anticancer agent 72 | ||
Anticancer agent 72 (compound 8c) effectively inhibits the K+ channel, displaying significant potential as an anticancer treatment. Additionally, it induces apoptosis, a programmed cell death process [1]. | |||
T12377L | PD-1-IN-17 (TFA) (1673560-66-1 free base) | PD-1-IN-17 (TFA) | Others |
PD-1-IN-17 TFA is a inhibitor of programmed cell death-1 (PD-1) . | |||
T80052 | Cathepsin B | ||
Cathepsin B, a cysteine protease, plays a role in various forms of programmed cell death, such as apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death [1]. | |||
T12377 | PD-1-IN-17 | PD-1/PD-L1 | |
PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM. | |||
T36046 | LH1306 | ||
LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 25 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation ... | |||
T73630 | PD1-PDL1-IN 1 TFA | ||
PD1-PDL1-IN 1 TFA (compound 16) is a potent inhibitor of programmed cell death 1 (PD-1), functioning as an immune modulator [1]. | |||
T81928 | Lipustobart | PD-1/PD-L1 | |
Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplastic activity [1]. | |||
T36047 | LH1307 | ||
LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation o... | |||
T63256 | PD-1-IN-17 TFA | ||
PD-1-IN-17 TFA is a potent inhibitor of programmed cell death-1 (PD-1), inhibiting 92% of splenocyte proliferation at a concentration of 100 nM. | |||
T77180 | Retifanlimab | ||
Retifanlimab, an anti-programmed cell death protein 1 (anti-PD-1) monoclonal antibody (mAb), is utilized in the research of gastroesophageal adenocarcinoma (GEA) [1]. | |||
T77178 | Pucotenlimab | ||
Pucotenlimab (HX008), a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting programmed cell death protein 1 (anti-PD-1), serves as a potential agent in tumor research [1]. | |||
T76714 | Sugemalimab | ||
Sugemalimab, a fully human, full-length, IgG4 monoclonal antibody (mAb) targeting programmed death ligand 1 (PD-L1), exhibits anticancer activities and is applicable in non-small cell lung cancer research [1]. | |||
T76936 | Budigalimab | ||
Budigalimab (ABBV 181; PR 1648817), a humanized IgG1 monoclonal antibody, specifically targets the programmed cell death 1 (PD-1) receptor. It features an Fc mutation to decrease interactions with the Fc receptor, thereb... | |||
T60776 | Anticancer agent 68 | ||
Compound 12, also known as Anticancer agent 68, functions as an anti-cancer agent by arresting cells at the G2/M phase and inducing programmed cell death. Moreover, it promotes tumor suppression by activating p53 and PTE... | |||
T80588 | Bintrafusp alfa | M7824,MSB0011359C | |
Bintrafusp alfa (M 7824), a pioneering bifunctional fusion protein, integrates the extracellular domain of TGF-βRII with a human IgG1 monoclonal antibody that inhibits the programmed cell death ligand. This compound is u... | |||
TP1947 | P110 | ||
Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen... | |||
T36034 | CAY10774 | ||
CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50= 15 nM in a homologous time-resolved fret (HTRF) assay).1It increases the activation of Jurkat... | |||
T82508 | Eciskafusp alfa | PD-1/PD-L1 | |
Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific stem-like PD-1+ TCF-1+ CD8+ T cells to differentiate into a ... | |||
T83724 | TPP-1 hydrochloride | Targeting PD-L1 Peptide | |
TPP-1, a peptide inhibitor, targets the interaction between programmed cell death protein 1 (PD-1) and its ligand (PD-L1), binding specifically to PD-L1 with a dissociation constant (Kd) of 94.67 nM. At a concentration o... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05815 | PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated | Canine | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-04342 | PD-1 Protein, Canine, Recombinant (His) | Canine | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05260 | PD-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05395 | PD-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00996 | PD-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00897 | PD-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05079 | PD-1 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-04898 | PD-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-04346 | PD-L2 Protein, Human, Recombinant (His) | Human | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-04957 | PD-L2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-05827 | PD-L2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-00253 | PD-1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00633 | PD-1 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-04341 | PD-1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00233 | PD-1 Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05295 | PD-1 Protein, Cynomolgus, Recombinant (hFc & Avi), Biotinylated | Cynomolgus | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-03717 | PD-1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00250 | PD-1 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-03404 | PD-L2 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-06838 | PD-L2 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-06819 | PD-L2 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-04225 | PD-L2 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-04223 | PD-L2 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-03738 | PD-L2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-04967 | PD-1 Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPJ-00181 | PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell pr... | |||
TMPY-05282 | PD-L2 Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-02436 | PD-L2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-02352 | PD-L2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPJ-00182 | PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | Human Cells |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, C... | |||
TMPJ-00183 | PD-L1 Protein, Human, Recombinant (Flag) | Human | Human Cells |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, C... | |||
TMPJ-00718 | AIF Protein, Human, Recombinant (His) | Human | E. coli |
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is t... | |||
TMPY-06336 | PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05619 | PD-1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-06682 | PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00896 | PD-1 Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPJ-00661 | PDCD5 Protein, Human, Recombinant (His) | Human | E. coli |
Programmed Cell Death Protein 5 (PDCD5) is a member of the PDCD5 family. PDCD5 is expressed in tumor cells during apoptosis, independent of apoptosis-inducing stimuli. This protein may function in the process of apoptosi... | |||
TMPJ-00637 | PD-L1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | Human Cells |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, C... | |||
TMPJ-00638 | PD-L1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Human Cells |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, C... | |||
TMPY-05613 | PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-00120 | PD-L2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPY-06281 | PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ... | |||
TMPJ-01300 | PDCD10 Protein, Human, Recombinant | Human | E. coli |
Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is req... | |||
TMPY-04343 | PD-L1 Protein, Human, Recombinant (His) | Human | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res... | |||
TMPY-05208 | PD-L1 Protein, Human, Recombinant | Human | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res... | |||
TMPY-04949 | PD-L1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res... | |||
TMPY-03670 | PD-L1 Protein, Cynomolgus/Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res... | |||
TMPY-04345 | PD-L1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res... | |||
TMPY-00237 | PD-L1 Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res... | |||
TMPY-01155 | PD-L1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res... | |||
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